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The mitochondrial SERAT2;2 is responsible of 80% of SERAT activity (Watanabe et al., 2008)

& Brown-Harding, H

While methylfolate is generally the preferred supplemental form because it bypasses the activation pathway, it is incorrect to conclude that folic acid has no place in clinical practice

doi: 10.1016/j.jcf.2017.10.013 25 MirnaghiFSCaudyAA