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If you find it hard to remember to take them on an empty stomach in the morning, taking them with a light meal is far better than skipping them entirely

I also have slight chest pressure, I have had this before after a long time without B12 and then having too much at once

The Right Dose for Skin Results Best Time to Take Glutathione Morning, Night or With Food

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Take your dose 2 to 3 hours after dinner so that your stomach is relatively empty