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Together, these agents reflect the growing importance of individualized, multi-targeted strategies in PD management

h , Volcano plots of the fold change in mitochondrial metabolite abundance (log 2 ) versus P values (-log) from HEK-293T SLC25A39 knockout cell line expressing a vector control or SLC25A40 cDNA

2021), which are very different from other cell death modes, including apoptosis, necrosis, and autophagy (Jin et al

Another consideration is botanical drugdrug interactions: many patients will use natural products alongside standard medications, so understanding interactions is critical

Currently, some countries are considering to ban it entirely (like Denmark) and the permitted use level is very low (under 0.01%)