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This highlights the importance of cautious dosage determination and rigorous monitoring during administration to prevent any adverse outcomes that might arise from an overzealous eradication of senescent cells

When combined with antibiotics, thalidomide lowered TNF- levels, reduced leukocytosis, and alleviated brain pathology, resulting in markedly improved survival in a rabbit model of acute M.tb CNS infection [144]

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Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial