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They have inflows and outflows, and only a fraction of the inflows could be diverted to a human water resource without affecting the lake

Repurposing of already approved drugs has been explored, for example, disulfiram, a drug traditionally used to treat alcohol dependence, can lower cystine levels in cystinotic cells, but has side effects that limit its use in cystinosis [151, 153]

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Instead, it participates in detoxification reactions and is recycled by the body

93 Impaired SIRT1 function decreases PPAR activity, leading to lipid metabolism disorders, increased hepatic lipid deposition, and aggravated inflammatory responses