Result and Discussion Overall structure of apo and ascorbate-bound OsDHAR The crystal structure of the native form of OsDHAR (UniProtKB code Q65XA0
A major function of vitamin C is to keep glutathione in its reduced form so that it can continue to provide free radical-quenching effects
Key Summary Yes, Vitamin C plays an important role in helping the body maintain and recycle glutathione
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Early reports that Kupffer cell-induced oxidant stress and peroxynitrite formation may cause APAP-induced injury [92, 93] were questioned as the data could not be reproduced [9496], NADPH oxidase-deficient mice were not protected [97, 98] and mitochondria in centrilobular hepatocytes were identified as the main source of superoxide and peroxynitrite under these conditions [72, 99]
