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Of youth and young adults who smoke, over half smoke menthol

However, in vivo exposure to e-cigarette aerosol for 1 month reduces the expression of TNF and IL-1 in lung-resident macrophages, along with reduced expression of Toll-like receptor 7 (TLR7), co-stimulatory molecules CD80 and CD86, and the transcription factor IRF7(28), suggesting that e-cigarette chemical exposures may lead to different immunophenotypes in the setting of multiple cell types interacting, leading to different signaling than that seen in isolated cell types

However, its important to remember that even nicotine-free vapes may carry some health risks

Its really not worth the effort with so many other great electronic cigarettes available out there