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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

Local injections near the tendon, subcutaneous around the area, or oral forms

The mechanisms underlying these effects include modulation of the skin immune response by suppressing the production of inflammatory cytokines, such as interleukin (IL)-1 and tumor necrosis factor-alpha (TNF), and increasing the production of anti-inflammatory cytokines, such as IL-4 and IL-10, therefore promoting a favorable environment for tissue healing and reducing inflammation (Routley and Ashcroft, 2009

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Its safety, efficacy, and pharmacological profile in humans have not been established