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For most facial serums, moisturizers, and hair tonics, a concentration of 1% to 3% is the sweet spot

Methylcobalamin (Vitamin B12): Supports nerve function and the production of DNA and red blood cells

Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs

2003, titled The role of thiamine deficiency in alcoholic brain disease. When used in detox, thiamine helps protect neural tissue, supports mitochondrial function, and prevents irreversible brain injury