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Malignant melanoma, resulting from the intricate interaction of developmental signals and genetic events, is further aggravated by UV radiation [89,90,91]

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Moreover, patients with ESKD show an expansion of proteolytic bacteria involved in uremic toxins metabolism but a reduced relative abundance of carbohydrate-fermenting bacteria such as Lactobacillacea e and Prevotellaceae families (Wong et al., 2014)