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While presenting symptoms are often vague, anorexia (loss of appetite), dehydration, weight loss and lethargy may be observed

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Notably, primates who were treated at an adipotide dose of 0.43mg/kg daily for four weeks [1]: Exhibited normal levels of activity without any overt clinical signs of nausea, vomiting, or food aversion Showed normal lipid profiles that did not vary throughout the study Registered higher levels of serum creatinine from adipotide doses of 0.25mg/kg Increased urine, with mild dehydration being reported at the highest adipotide dose levels Most changes in the primates serum and urine were reversed within 28 days following discontinuation of treatment [1]

Institute of Medicine says, Since 10-30% of older people may malabsorb food-bound B12, it is advisable for those older than 50 to meet their RDA mainly by consuming foods fortified with B12 or a B12-containing supplement (IOM, 1998, p

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