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Although ROS generation may not be an essential factor for aging (Lpez-Otn et al., 2013), they are more likely to exacerbate age-related diseases progression via oxidative damage and interaction with mitochondria (Dias et al., 2013)

Term neonates with infection and shock display high cortisol precursors despite low levels of normal cortisol

Taken together, the data suggest that testing FM patients for elevated levels of anti-SGC IgG may be useful to stratify patients for therapies that interfere with antibody function such as B cell depleting drugs, IVIg, or plasmapheresis