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However, it is noted that the clinical outcome of ACI is still variable (Andriolo et al., 2017), and the reasons have not been fully demonstrated

GHK-Cu (glycyl-l-histidyl-l-lysine copper) is a peptide composed of three amino acids: glycine, histidine, and lysine

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RANTES, regulated on activation, normal T-cell expressed and secreted

Furthermore, TSPP has several drawbacks that can limit the validity of data obtained: i ) the sub-micromolar Kd value of the TSPP-copper complex may not provide accurate data at the point of/or above saturation