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"Dietary Reference Intakes for Japanese 2010: Water-Soluble Vitamins" Journal of Nutritional Science and Vitaminology 2013(59):S67S82

In D-galactose-induced aging mice, oral administration of the product significantly increased NAD+ levels in liver and adipose tissue, activated mitochondrial energy metabolism pathways, improved insulin sensitivity, lowered blood glucose and lipid levels, reduced visceral fat accumulation, and increased energy expenditure, alleviating fatigue and abnormal body weight associated with aging

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