Additionally, we find that the decrease in glutamate brought by acivicin could be rescued by administration of pyroglutamate (5-oxoproline), a downstream metabolite in the glutathione pathway that is a precursor of glutamate (Fig
5 mg/mL concentration: 50 units = 2.5 mg (starting dose, weeks 1-4) 10 mg/mL concentration: 50 units = 5 mg (moderate dose, weeks 5-8) 15 mg/mL concentration: 50 units = 7.5 mg (mid-range dose, weeks 9-12) 17 mg/mL concentration: 50 units = 8.5 mg (between standard tiers) 20 mg/mL concentration: 50 units = 10 mg (high dose, weeks 13-16) 30 mg/mL concentration: 50 units = 15 mg (maximum dose, week 21+) Notice the pattern
Mittag, J., Behrends, T., Hoefig, C., Vennstrm, B
Structurally derived from angiotensin IV
This last qualifier cant be emphasized enough