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Free Radic Biol Med 124:110121

The reclassification to Category 2 may serve as a catalyst for pharmaceutical companies and research institutions to invest in the rigorous clinical trials required for formal FDA approval

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The nose-to-brain pathway provides a non-invasive alternative to other routes for the delivery of macromolecular therapeutics

Clinical studies indicate that osteogenic potential negatively correlates with age, with younger donors displaying higher osteogenic marker expression