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Vitamin D toxicity can also cause gastrointestinal distress, and it can lead to a buildup of calcium that can lead to bone and kidney pain

doi: 10.1055/a-1528-2721, 10

It has been observed that repeated doses of DCA resulted in loss of GSTZ1-1 protein and activity, probably due to post-translationally modifications of the enzyme 85

(2005), 23 ME/CFS (meeting CDC-1994 criteria) and 42 healthy control (serum), similarly evaluated tryptophan levels