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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

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Knockout mutants of odc were arrested in the Y-form and were unable to undergo the Y-H transition [110]

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Beyond its metabolic role, FBP1 exhibits non-canonical functions in regulating mitosis, controlling cell cycle progression, and modulating c-Myc-dependent transcriptional programmes, thereby contributing to the persistence of drug-resistant cell populations on multiple fronts [100]

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