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The senolytic demonstrates preferential elimination of transforming growth factor- (TGF-)-induced myofibroblasts while sparing normal fibroblasts, showing selectivity for pathological senescent cells driving fibrosis

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Following ischemic onset, extracellular zinc levels increased and were synchronous with glutamate release

Abstract Introduction 5-oxoproline (pyroglutamic acid), an organic acid intermediate of the gamma-glutamyl cycle, is a rare cause of high anion gap metabolic acidosis