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One/Twice a week Reconstitute the solution in the powder vial & liquid ampoule with 100ml-500ml of Saline for injection by means of a syringe with an appropriate needle through IV

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Increased intracellular calcium inhibits enzymes responsible for the distribution of phospholipids in plasma membranes and the release of cytochrome C and apoptosis-inducing factors, triggering neuronal apoptotic death, suppressing neurotransmission, and cognitive dysfunction (Bezprozvanny and Mattson 2018)

M.BendzB.et al (2021)

As a cofactor of dioxygenases, insufficiency of -KG should in theory affect all 2OGDDs