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Glucose-6-Phosphate Dehydrogenase: G6PD The glucose-6-phosphate dehydrogenase gene (symbol: G6PD) is located on the X chromosome (Xq28) and is composed of 14 exons that generate three alternatively spliced mRNAs

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In particular, up-regulation of the transcripts for the rate-limiting enzyme of the TCA cycle, 2-oxoglutarate dehydrogenase (OGDH), and for the TCA-cycle-affiliated proteins, such as subunits of pyruvate dehydrogenase (PDH) and branched chain 2-oxo acids dehydrogenase (BCODH) is observed

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