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doi: 10.1016/s0196-9781(03)00040-8

Yin W, Cheng W, Shen W, Shu L, Zhao J, Zhang J et al

The use of retinoids in the treatment of skin lesions and prevention of signs of skin aging-a systematic review[J]

Like many therapeutic peptides, it may require daily (or near-daily) administration, as in the previously referenced mouse and rabbit studies.12 17 Moreover, as a preventive or a drug for managing chronic health conditions, treatment ought to be ongoing and may involve periodic breaks in dosing (cycling), which is also common with many therapeutic peptides

This process involves enzymes like NADPH oxidase and myeloperoxidase, which produce superoxide and hypochlorous acid (HOCl), respectively