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Figure 2 In recent years, Candida -related breakthrough BSIs have emerged as complex clinical challenges, often occurring despite standard antifungal therapy

Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection

The group taking 0.5mg of tesofensine experienced an average weight loss of 13-14kg during this period, which was significantly more than the placebo group

Informed consent was obtained from all enrolled participants in the study