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The most commonly reported side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

van der Kooij, M

On one hand, studies using different animal modelshydraulic impact (vertical force transmission) versus CCI (rotational force transmission)often produce inconsistent results, highlighting the need to examine how model-dependent differences affect clinical translation

The suppression of specific metabolism may represent an attractive therapeutic strategy for the treatment of ovarian cancer [41]