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In cell cultures and mouse models of HD as well as in patient samples, the levels of CSE are drastically diminished, due to the sequestration of SP1 by mHtt (Paul et al ., 2014)

Given the rising global prevalence of e-cigarette and heated tobacco product use, particularly among younger populations, there is an urgent need for longitudinal studies assessing their hepatotoxic potential, including device- and flavor-specific effects

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Van Konynenburg, RA (April 21, 2012)