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Slower Lung Function Decline When someone with COPD continues to smoke, lung function declines much faster over time

In the final model, we included a spline on age, random slope on age by study and the bias covariate encoding exposure definition (that is, current, former and ever smokers), which was picked by the variable selection algorithm 28,29

If the applicant seeks waiver of prior notice under 191.91, any documentation submitted to Customs to comply with this section will be included in the request under 191.91

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