GSH can be exhausted via inhibiting SLC7A11 by traditional drugs (e.g., sorafenib and sulfasalazine (SAS)) or novel compounds (e.g., erastin), thus inducing ferroptosis (Zhang et al., 2018), tumor protein 53 (TP53) (Jiang et al., 2015), nuclear factor E2 related factor 2 (NFE2L2/Nrf2) (Sun et al., 2016)
In a primary prevention trial, the goal is to reduce exposure to aflatoxins in the diet
Use as needed to maintain hydration, especially in harsh weather conditions
This is even more important for those with any hormonal conditions/symptoms such as PCOS, endometriosis, adenomyosis, stress, anxiety, migraines or poor sleep
Oxidative stress is one of the many causes of diseases likediabetes, arthritis and cancer