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Folinic acid (leucovorin) shows promise in children with autism spectrum disorder (ASD) who have folate receptor alpha (FR) autoantibodies

However, in pathological or abnormal physiological states, the equilibrium is disturbed

The "key targets" predicted by AI may not accurately capture the essence of this network regulation

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Emotional stress and Estrogen (COMT and MAOA) Slower variants of these genes contribute to potentially higher levels of dopamine, norepinephrine and serotonin, which increases vulnerability to stress and irritability