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In addition, using the SwissADME software, additional properties were evaluated, including gastrointestinal absorption (GI a), bloodbrain barrier permeability (BBB p), potential inhibition or substrate activity for Pglycoprotein (Pgp), as well as inhibition of the main CYP450 isoforms, specifically 1A2, 2C9, 2C19, 2D6, and 3A4

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doi: 10.1517/13543784.15.8.933 [DOI] [PubMed] [Google Scholar] 85.Feix SJB

Preliminary comparison of real time QPCR with cytogenetic karyotype, hypermetaphase FISH and western blot analysis in CML patients in clinical remission