defense substances, against this relevant binding protein TC II is considered to be a possible cause (Takahashi et al., 2013)
2009;20(6):12105 Ho MJ, Bellusci A, Wright JM
Other promising agents include natural compounds (e.g., genistein, auraptene, osthole, sulforaphane) and strategies that restore NAD + levels (NMN, NR), which collectively target mitochondrial dysfunction, ER stress, and insulin resistancekey features of PCOS-related oxidative stress [28,114,124,137,138]
This is important because unchecked oxidative stress is associated with so many diseases including cancers, neurodegenerative diseases such as Parkinsons and Alzheimers, and heart disease that it can aptly be considered a killer
If Phase II is too slow, the reactive Phase I intermediates accumulate and cause oxidative damage, DNA mutations, and cellular inflammation