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3 The role of NAC in bone microenvironment 3.1 NAC promotes the osteogenic differentiation of stem cells in the bone immune microenvironment Among the MSCs sourced from various tissues, bone marrow-derived mesenchymal stem cells (BMSCs) and adipose-derived mesenchymal stem cells (AMSCs) are most widely used in bone tissue engineering (Hoang et al., 2022

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Genet 156 , 215224 (2011)