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2.3 General description of the method The procedure included the following: Clinical examination of temporomandibular joints and muscles of the stomatognathic system according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)axes I and II ( Saliva and blood collection

These include: Smoking Excessive intake of sugar and refined carbohydrates Exposure to ultraviolet rays Signs of Collagen Deficiency The signs of collagen deficiency are visible to the naked eye

4 In addition, NAC must be administered at high doses due to its low bioavailability, but high-dose NAC may increase the risk of adverse reactions

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