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In the context of early brain injury following subarachnoid hemorrhage (SAH), topiramate significantly reduced the elevated levels of TNF-, IL-1, and IL-6 induced by SAH, suggesting that topiramate may exert neuroprotection via its anti-inflammatory effects (Tian et al., 2015)

Any misstep in the mixing process can degrade the peptides, alter their concentrations, and ultimately render an entire experiment's data useless

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The elevated B12 appears to be a consequence of disease activity, likely resulting from increased production of B12-binding proteins by tumor cells or from liver involvement in the cancer process

(30) was used, adapted to a 96-well microplate format