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We also downloaded level 3 DNA methylation data (i.e., JHC_USC HumanMethylation450K) 60, 61 and level 3 RNA expression data (i.e., UNC IlluminaHiSeq_RNASeqV2) 60, 61 on lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) from the large-scale database of TCGA 62 to provide validation for the identified smoking-related oncogenes

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Right now, high insulin price is the rallying cry, but cancer drugs are always included in the conversation and financial toxicity has become a widely recognized issue

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Figure 3 shows the statistically significant relationship between adjusted ITT Index score and ITT as share of total cigarette consumption (p value: 0.04)