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Free Radic Biol Med (2021) 176:31221

A comprehensive diagnostic workup includes most, if not all, of the following procedures: Electrodiagnostic tests including electromyography (EMG) and nerve conduction velocity (NCV) Blood and urine studies including high resolution serum protein electrophoresis, thyroid and parathyroid hormone levels and 24-hour urine collection for heavy metals Spinal tap X-rays, including magnetic resonance imaging (MRI) Myelogram of cervical spine Muscle and/or nerve biopsy A thorough neurological examination These tests are done at the discretion of the physician, usually based on the results of other diagnostic tests and the physical examination

Topical application of L-carnitine is generally well tolerated, with minimal risk of irritation

Expanded Access (Compassionate Use): This narrow pathway allows physicians to request investigational drugs through a single-patient Investigational New Drug (IND) application

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