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Materials and methods Animal experiments C57BL/6J aged (20 months) male mice and mast cell deficient c-Kit wsh /cKit wsh mice (12 months) were housed in a specific pathogen-free facility (light cycle 12/12 h light/dark)

By following the guidelines discussed in this article, researchers can make informed decisions that maximize the stability and efficacy of their peptides, ultimately contributing to the success of their work in the lab.

B) antioxidant group 1 (VC + VE group) vitamin C (400 mg/kg b.w) and vitamin E (50 mg/kg b.w)

(86) demonstrated that the main histopathological changes in inflammation and bone structure happened during the first 2 weeks on the onset of clinical symptoms in the joint, and once inflammation declined, it is the bone remodeling that predominated

Ethics declarations Ethical approval The medical ethics committee of Hospital Universitari Arnau de Vilanova approved the protocol (CEIC/2273)