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The Need for New Formulations Because of these quite dramatic and potentially efficacious effects, and the urgency of the COVID19 pandemic, in addition to simply repurposing the original oral tablets, there have been efforts to develop new formulations and routes of administration for niclosamide, to validate them in preclinical studies, and clinically test niclosamide for COVID-19 (see this reference to clincaltrials.gov (35))