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The original Review included two RCTs involving more than 600 participants, and found that electronic cigarettes containing nicotine may increase the chances of stopping smoking within six to 12 months, compared to using an electronic cigarette without nicotine

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We found a moderate correlation of CPD and urinary cotinine, as Pearsons r was 0.4 for both, men and women (Table 2)

Among the incriminating substances of smoking is nicotine also contained in some vape liquids, which help smokers quit smoking during the first stage and substances such as tar, arsenic, formaldehyde benzene, etc

[26] In 2010 the age-standardised mortality rate was 3.8 deaths per 1000 (down from 4.8 in 2000) and the infant mortality rate for the total population was 5.1 deaths per 1000 live births