B12 absorption depends heavily on intrinsic factor binding in the stomach and transit time through the small intestine
The B12, whether methylcobalamin or cyanocobalamin, goes into the muscle and into your system without depending on a digestive step that may not be working well for you
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[3] Those taking high-dose oral supplements without medical supervision also face increased risk
Without enough B12, red blood cells can become large and irregular (megaloblastic anemia), which reduces their ability to carry oxygen efficiently