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Monitoring of electrolytes, including sodium, potassium, bicarbonate, magnesium, and phosphorus, is important, and the presence of acidosis is a risk factor for poor outcome in acute liver failure and has been incorporated into some prognostic models

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In summary, the development of pharmacological agents that promote itaconate production could potentially mitigate pathological inflammatory responses and prevent severe lung injury associated with TB progression

These changes were not observed in the placebo group