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Nicotine can affect you physically in the following ways: Dependence: The body can adapt regular nicotine intake and experience withdrawal once that level decreases

[1] Smoking in the US military from 1917 to 1975 [edit] With the American entry into World War I in 1917, cigarette use increased dramatically among United States military personnel

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Journal of Graduate Medical Education

In the oral mucosa, where the ageing epithelial cells move faster to the surface compared to skin, a similar defence-mechanism seems to be present, cleaning the mucosa from different toxic chemicals penetrating the epithelium