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A change in GSH levels is important when assessing toxicological responses and an indicator of oxidative stress, potentially leading to apoptosis or cell death

The uptake efficiency of these fertilizers by plants is generally 3050%, leading to economic losses and large environmental impacts, due to large quantities of the fertilizer being lost to water bodies and the atmosphere (Adesemoye and Kloepper, 2009)

However, as with any medical intervention, there are important contraindications to consider

Duration of action can be about 6-12 hours after onset of effect

A more recently established target in the antioxidant pathway is BACH1, which serves as a negative regulator of NRF2