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Mulhall J, King R, Glina S, Hvidsten K

The activity of eNOS is tightly regulated by multiple intracellular process including posttranslational modification, phosphorylation and proteinprotein interactions 14,15

Yet that process comes with trade-offs

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Combining with the structural information, this technique could be used to identify positions where the olefinic amino acids could be introduced along the nonbinding interface to ultimately form the hydrocarbon staple (Figure 2C)