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Do the triggers first happen inside the body (from bacteria or a virus), outside the body (environmental), or a combination of both

PMID: 8946988 Amano J, Suzuki A, Sunamori M

Likewise, SARS-Cov-2 infection and acute COVID-19 are accompanied by an inflammatory response [29], increased MPO activity [45], indicants of oxidative damage [46,47,48] and increased NO production including increased levels of nitrotyrosine [49], and lowered antioxidant defenses (ANTIOX) as indicated by reduced TAC levels [45, 49], Gpx [50], and zinc [51]

This was the upper limit of quantitation of assays performed in the early days of research regarding paracetamol poisoning and has empirically been maintained as the definition for liver injury since then *

Jogl G, Hsiao YS, Tong L