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Cardiovascular effects: Glucagon receptor agonism (via retatrutide) and GLP-1 receptor agonism have been associated with modest increases in heart rate as a class effect

The key difference comes down to bioavailability, which is how much of a nutrient your body can actually absorb and use

Practically, this means the ODT requires higher doses to achieve comparable effects, and individual responses will vary more than with injections

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