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A Cochrane review comparing oral and intramuscular B12 found comparable effects on blood levels, and the same principle of good absorption applies to the subcutaneous route

This means that hydroxycobalamin stays in the body for longer periods of time and can provide sustained levels of vitamin B12, which may be beneficial for individuals with severe or chronic vitamin B12 deficiency

Clinical Update 3/21/2020 When to Eat Protein Some evidence indicates that it is best to distribute protein across meals throughout the day to maximize protein production in muscle

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