Disclosure of interest: Xiao Wang: nothing to disclose E-Posters - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P2515 - ESOC25-1203 GUT MICROBIOTADEPENDENT TRIMETHYLAMINE N-OXIDE AND COGNITIVE FUNCTION OVER THREE YEARS AFTER MILD-TO MODERATE ISCHEMIC STROKE - PROSCIS B Thomas Liman 1 , Naomi Giesers 2 , Arash Haghikia 3 , Ulf Landmesser 4 , Stanley Hazen 5 , Matthias Endres 6 1 University of Oldenburg, Charit Universittsmedizin Berlin, Oldenburg, Germany, 2 University of Oldenburg, Oldenburg, Germany, 3 Ruhr University Bochum, Bochum, Germany, 4 Charit Universittsmedzin Berlin, Berlin, Germany, 5 Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, United States, 6 Charit Universittsmedizin Berlin, Dept of neurology, Berlin, Germany Background and Aims: Gut microbiotadependent metabolites, in particular trimethylamine n-oxide (TMAO) have been identified as promoters of atherosclerosis

Unopened Vitamin B-12 can be stored out of the refrigerator as long as the storage place maintains a stable temperature below the recommended 25c / 77f
Nicolson R, Lenane M, Hamburger SD, Fernandez T, Bedwell J, Rapoport JL (2000)
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A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults