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Neelakantan H, Vance V, Wetzel MD, Wang HY, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice. Biochem Pharmacol. 2018 Jul;154:161-171. doi: 10.1016/j.bcp.2018.05.003. Epub 2018 May 5. PMID: 29738706; PMCID: PMC6015571

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Do not administer this drug to the following patients: 1) Patients with hypersensitivity to the components of this drug 2) Patients with hypercalcemia, hypercalciuria 3) Patients with calcium oxalate stones 4) Patients with renal impair 5) Patients who are immobilized in a hospital bed 6) Sarcoidosis 7) Patients with pseudoparathyroidism 3

Our bodies take oxidative hits every single day from stress, poor sleep, pollution, processed foods, pesticides, and even normal metabolism