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Furthermore, Gln metabolism contributes to chemotherapy resistance in prostate cancer cells by modulating drug efflux, particularly through the upregulation of the ATP-binding cassette transporter ABCB1 (224)

It means the therapy may be worth discussing when symptoms suggest that local airway support could help, and when the patient is stable enough to tolerate inhaled treatment

1 (De Gruyter: Berlin, 2014)

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