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108,109 The decrease in mitochondrial membrane potential induces PINK1 aggregation and autophosphorylation on the outer mitochondrial membrane, which recruits Parkin to initiate the PINK1-Parkin mitophagy pathway to remove damaged mitochondria

Evaluation of neuropathological features in the SOD1-G93A low copy number transgenic mouse model of amyotrophic lateral sclerosis

Ultra-high resolution structures can provide an unparalleled level of detail, showing individual atoms and their arrangement within the protein molecule, capturing the dynamic nature of proteins and showing their regions with multiple conformations, as well as allowing evaluation of hydrogen bonding and solvent networks